On August 10, 2008, Hayes' wife found him on the floor near a treadmill inside his home located just east of Memphis, Tennessee. A Shelby County, Tennessee sheriff's deputy responded to Hayes' home. He was taken to Baptist Memorial Hospital in Memphis, where he was pronounced dead at 2:08pm, at the age of 65. The cause of death was not immediately known.
This is such a tragic and twisted series of events that Isaac Hayes passed two days after Bernie Mac did being that they were suppose to be co-starring in a new movie along side Samuel L Jackson.